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Cranberry fruit powder (Flowens™)improves lower urinary tract symptoms in men: a double-blind, randomized, placebo-controlled trial

Posted: 
September 28, 2015
Authors: 
Vidlar A, Student Jr V, Vostalova J, Fromentin E, Roller M, Simanek V, Student V
Journal: 
World J Urol DOI 10.1007/s00345-015-1611-7
Abstract: 

Lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia increase with age. To date, several medications are available to treat LUTS, including herbal remedies which offer less side effects but lack robust efficacy studies.
This 6-month, randomized, double-blind, placebo-controlled study aimed at evaluating the dose effect of 250 or 500 mg cranberry powder (Flowens™) on LUTS and uroflowmetry in men over the age of 45. A total of 124 volunteers with PSA levels After 6 months, subjects in both Flowens™ groups had a lower IPSS (-3.1 and -4.1 in the 250- and 500-mg groups, p = 0.05 and p Flowens™ showed a clinically relevant, dose-dependent, and significant reduction in LUTS in men over 45.